| Reference |
|---|
Mani K, El Hakim Y, Branyan T, Samiya N, Pandey S, Grimaldo M, et al. Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke. Brain Behav Immun. 2023;107:345-360 pubmed publisher |
Viladomiu M, Khounlotham M, Dogan B, Lima S, Elsaadi A, Cardakli E, et al. Agr2-associated ER stress promotes adherent-invasive E.coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis. Cell Rep. 2022;41:111637 pubmed publisher |
Watanabe S, Kobayashi S, Ogasawara N, Okamoto R, Nakamura T, Watanabe M, et al. Transplantation of intestinal organoids into a mouse model of colitis. Nat Protoc. 2022;17:649-671 pubmed publisher |
Han Y, Villarreal Ponce A, Gutiérrez G, Nguyen Q, Sun P, Wu T, et al. Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1. Cell Rep. 2022;38:110240 pubmed publisher |
Knight J, Vlahov N, Gay D, Ridgway R, Faller W, Proud C, et al. Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K. elife. 2021;10: pubmed publisher |
Tarquis Medina M, Scheibner K, González García I, Bastidas Ponce A, Sterr M, Jaki J, et al. Synaptotagmin-13 Is a Neuroendocrine Marker in Brain, Intestine and Pancreas. Int J Mol Sci. 2021;22: pubmed publisher |
Taylor S, Ramsamooj S, Liang R, Katti A, Pozovskiy R, VASAN N, et al. Dietary fructose improves intestinal cell survival and nutrient absorption. Nature. 2021;597:263-267 pubmed publisher |
Leach J, Vlahov N, Tsantoulis P, Ridgway R, Flanagan D, Gilroy K, et al. Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis. Nat Commun. 2021;12:3464 pubmed publisher |
B xf6 ttcher A, B xfc ttner M, Tritschler S, Sterr M, Aliluev A, Oppenl xe4 nder L, et al. Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates. Nat Cell Biol. 2021;23:23-31 pubmed publisher |
Bilotta A, Ma C, Yang W, Yu Y, Yu Y, Zhao X, et al. Propionate Enhances Cell Speed and Persistence to Promote Intestinal Epithelial Turnover and Repair. Cell Mol Gastroenterol Hepatol. 2021;11:1023-1044 pubmed publisher |
Li Y, Chen M, Hu J, Sheng R, Lin Q, He X, et al. Volumetric Compression Induces Intracellular Crowding to Control Intestinal Organoid Growth via Wnt/β-Catenin Signaling. Cell Stem Cell. 2021;28:63-78.e7 pubmed publisher |
Claudinot S, Sakabe J, Oshima H, Gonneau C, Mitsiadis T, LITTMAN D, et al. Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence. Nat Commun. 2020;11:5645 pubmed publisher |
Zwiggelaar R, Lindholm H, Fosslie M, Terndrup Pedersen M, Ohta Y, Díez Sánchez A, et al. LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Sci Adv. 2020;6: pubmed publisher |
Zhang X, Bandyopadhyay S, Araujo L, Tong K, Flores J, Laubitz D, et al. Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration. JCI Insight. 2020;5: pubmed publisher |
Han T, Goswami S, Hu Y, Tang F, Zafra M, Murphy C, et al. Lineage Reversion Drives WNT Independence in Intestinal Cancer. Cancer Discov. 2020;10:1590-1609 pubmed publisher |
Zhang M, Haughey M, Wang N, Blease K, Kapoun A, Couto S, et al. Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. PLoS ONE. 2020;15:e0229445 pubmed publisher |
Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed publisher |
Singh A, Hung Y, Shanahan M, Kanke M, Bonfini A, Dame M, et al. Enteroendocrine Progenitor Cell-Enriched miR-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent Manner. Cell Mol Gastroenterol Hepatol. 2020;9:447-464 pubmed publisher |
Wang X, Han Y, Wang M, Bo C, Zhang Z, Xu L, et al. Wnt Signaling Protects against Pacl*taxel-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea In Vitro. Biomed Res Int. 2019;2019:7878906 pubmed publisher |
Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed publisher |
Schatoff E, Goswami S, Zafra M, Foronda M, Shusterman M, Leach B, et al. Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition. Cancer Discov. 2019;9:1358-1371 pubmed publisher |
Dickinson K, Hammond L, Karner C, Hastie N, Carroll T, Goodyer P. Molecular determinants of WNT9b responsiveness in nephron progenitor cells. PLoS ONE. 2019;14:e0215139 pubmed publisher |
Meng Z, Gwag T, Sui Y, Park S, Zhou X, Zhou C. The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling. JCI Insight. 2019;4: pubmed publisher |
Chen F, Yang W, Huang X, Cao A, Bilotta A, Xiao Y, et al. Neutrophils Promote Amphiregulin Production in Intestinal Epithelial Cells through TGF-? and Contribute to Intestinal Homeostasis. J Immunol. 2018;: pubmed publisher |
Smith N, Swain J, Davies P, Gallagher A, Parappilly M, Beach C, et al. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5-and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol. 2018;6:79-96 pubmed publisher |
Boyd M, Thodberg M, Vitezic M, Bornholdt J, Vitting Seerup K, Chen Y, et al. Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies. Nat Commun. 2018;9:1661 pubmed publisher |
Kim M, Xia B, Suh H, Lee S, Jun S, Lien E, et al. PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis. Dev Cell. 2018;44:582-596.e4 pubmed publisher |
Takahashi T, Shiraishi A, Murata J. The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice. Int J Mol Sci. 2018;19: pubmed publisher |
Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, et al. Development of a functional thyroid model based on an organoid culture system. Biochem Biophys Res Commun. 2018;497:783-789 pubmed publisher |
Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher |
Scavuzzo M, Yang D, Borowiak M. Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells. Sci Rep. 2017;7:10810 pubmed publisher |
Moorefield E, Andres S, Blue R, Van Landeghem L, Mah A, Santoro M, et al. Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells. Aging (Albany NY). 2017;9:1898-1915 pubmed publisher |
Feng Q, Bonder E, Engevik A, Zhang L, Tyska M, Goldenring J, et al. Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy. J Cell Sci. 2017;130:2491-2505 pubmed publisher |
Peck B, Mah A, Pitman W, Ding S, Lund P, Sethupathy P. Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status. J Biol Chem. 2017;292:2586-2600 pubmed publisher |
Attayek P, Ahmad A, Wang Y, Williamson I, Sims C, Magness S, et al. In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment. PLoS ONE. 2016;11:e0153795 pubmed publisher |
Morrison G, Scognamiglio R, Trumpp A, Smith A. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016;35:356-68 pubmed publisher |
Calderon Gierszal E, Prins G. Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure. PLoS ONE. 2015;10:e0133238 pubmed publisher |
Barrett C, Reddy V, Short S, Motley A, Lintel M, Bradley A, et al. Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage. J Clin Invest. 2015;125:2646-60 pubmed publisher |
Caruso M, Ferranti F, Corano Scheri K, Dobrowolny G, Ciccarone F, Grammatico P, et al. R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis. PLoS ONE. 2015;10:e0124213 pubmed publisher |
Moon C, Zhang W, Ren A, Arora K, Sinha C, Yarlagadda S, et al. Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. J Biol Chem. 2015;290:11246-57 pubmed publisher |
Dow L, Fisher J, O Rourke K, Muley A, Kastenhuber E, Livsh*ts G, et al. Inducible in vivo genome editing with CRISPR-Cas9. Nat Biotechnol. 2015;33:390-394 pubmed publisher |
López Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman A, et al. Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development. 2015;142:41-50 pubmed publisher |
McElroy S, Castle S, Bernard J, Almohazey D, Hunter C, Bell B, et al. The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis. Am J Pathol. 2014;184:2768-78 pubmed publisher |
f*ckuda M, Mizutani T, Mochizuki W, Matsumoto T, Nozaki K, Sakamaki Y, et al. Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon. Genes Dev. 2014;28:1752-7 pubmed publisher |
Capaldo C, Farkas A, Hilgarth R, Krug S, Wolf M, Benedik J, et al. Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins. Mol Biol Cell. 2014;25:2710-9 pubmed publisher |
Jurk D, Wilson C, Passos J, Oakley F, Correia Melo C, Greaves L, et al. Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat Commun. 2014;2:4172 pubmed publisher |
Mah A, Van Landeghem L, Gavin H, Magness S, Lund P. Impact of diet-induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1. Endocrinology. 2014;155:3302-14 pubmed publisher |
Skoczek D, Walczysko P, Horn N, Parris A, Clare S, Williams M, et al. Luminal microbes promote monocyte-stem cell interactions across a healthy colonic epithelium. J Immunol. 2014;193:439-51 pubmed publisher |
Wiener Z, Band A, Kallio P, Högström J, Hyvönen V, Kaijalainen S, et al. Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β. Proc Natl Acad Sci U S A. 2014;111:E2229-36 pubmed publisher |
Shi F, Hu L, Jacques B, Mulvaney J, Dabdoub A, Edge A. ?-Catenin is required for hair-cell differentiation in the cochlea. J Neurosci. 2014;34:6470-9 pubmed publisher |
Takemura N, Kawasaki T, Kunisawa J, Sato S, Lamichhane A, Kobiyama K, et al. Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome. Nat Commun. 2014;5:3492 pubmed publisher |
Bohórquez D, Samsa L, Roholt A, Medicetty S, Chandra R, Liddle R. An enteroendocrine cell-enteric glia connection revealed by 3D electron microscopy. PLoS ONE. 2014;9:e89881 pubmed publisher |
Matsumoto S, Fujii S, Sato A, Ibuka S, Kagawa Y, Ishii M, et al. A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures. EMBO J. 2014;33:702-18 pubmed publisher |
Li J, Chai B, Zhang W, Fritze D, Zhang C, Mulholland M. LGR4 and its ligands, R-spondin 1 and R-spondin 3, regulate food intake in the hypothalamus of male rats. Endocrinology. 2014;155:429-40 pubmed publisher |
Jin L, Feng T, Zerda R, Chen C, Riggs A, Ku H. In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice. Stem Cells Dev. 2014;23:899-909 pubmed publisher |
Huynh D, Akcora D, Malaterre J, Chan C, Dai X, Bertoncello I, et al. CSF-1 receptor-dependent colon development, homeostasis and inflammatory stress response. PLoS ONE. 2013;8:e56951 pubmed publisher |
Jin L, Feng T, Shih H, Zerda R, Luo A, Hsu J, et al. Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. Proc Natl Acad Sci U S A. 2013;110:3907-12 pubmed publisher |
Jarde T, Evans R, McQuillan K, Parry L, Feng G, Alvares B, et al. In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system. Oncogene. 2013;32:883-93 pubmed publisher |
Wong V, Stange D, Page M, Buczacki S, Wabik A, Itami S, et al. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol. 2012;14:401-8 pubmed publisher |
Tomaselli S, Megiorni F, Lin L, Mazzilli M, Gerrelli D, Majore S, et al. Human RSPO1/R-spondin1 is expressed during early ovary development and augments β-catenin signaling. PLoS ONE. 2011;6:e16366 pubmed publisher |
