R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
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66 results for "R-Spondin 1" in Products
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R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
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66 results for "R-Spondin 1" in Products
Catalog #: 4645-RS
(7)
Citations (101)
Images (5)
BA
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | Bioactivity |
(5)
Catalog #: 7150-RS
(3)
Citations (10)
Images (1)
BA
| Source: | CHO |
| Accession #: | NP_619624 |
| Applications: | Bioactivity |
Catalog #: RDC3238
Images (1)
Catalog #: 3474-RS
(5)
Citations (64)
Images (2)
BA
| Source: | E. coli |
| Accession #: | Q9Z132 |
| Applications: | Bioactivity |
(2)
Catalog #: MAB4658
Citations (1)
WB
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | Western Blot |
Catalog #: AF3474
Citations (5)
Images (2)
WB, IHC
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | Immunohistochemistry, Western Blot |
(2)
Catalog #: Qk006
Images (2)
BA
| Source: | E. coli |
| Accession #: | Q2MKA7.1 |
| Applications: | Bioactivity |
(2)
Catalog #: BT4645
Images (1)
BA
New Version Available - BT4645B
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | Bioactivity |
Catalog #: NBP1-77354
Citations (1)
Images (8)
ELISA, ICC/IF, IHC, WB
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot |
(8)
Catalog #: BT4645B
Images (2)
BA
Biotinylated
| Source: | CHO |
| Accession #: | Q2MKA7.1 |
| Applications: | Bioactivity |
(2)
Catalog #: AF4645
Citations (1)
Neut
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Block/Neutralize |
Catalog #: DY4645-05
(2)
Images (1)
ELISA
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
Catalog #: MAB3474
Images (1)
Neut
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #852010 |
| Applications: | Block/Neutralize |
Catalog #: NBP2-45636
Images (2)
IHC, WB
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | Immunohistochemistry, Western Blot |
(2)
Catalog #: NBP2-08561
Images (1)
WB
| Applications: | Western Blot |
-Western-Blot-NBP2-08561-img0001.jpg "R-Spondin 1 Products | Bio-Techne (13)")
Catalog #: NBP1-92357
Images (1)
IHC
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | Immunohistochemistry |
Catalog #: NBP3-21297
Images (1)
ICC/IF
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | Immunocytochemistry/ Immunofluorescence |
Catalog #: NBP1-92357PEP
AC
| Applications: | Antibody Competition |
Catalog #: NBP3-21297PEP
AC
| Applications: | Antibody Competition |
Catalog #: NBP1-77354PEP
AC
| Applications: | Antibody Competition |
Catalog #: NBP1-77354MFV610
Images (1)
ELISA, ICC/IF, IHC, WB
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot |
Catalog #: NBP1-77354AF647
Images (1)
ELISA, ICC/IF, IHC, WB
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot |
Catalog #: NBP1-77354AF594
Images (1)
ELISA, ICC/IF, IHC, WB
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot |
Catalog #: NBP1-77354V
Images (1)
ELISA, ICC/IF, IHC, WB
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot |
Catalog #: NBP1-77354AF350
Images (1)
ELISA, ICC/IF, IHC, WB
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot |
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